Exclusion of inflammation in the differential diagnosis of an elevated prostate-specific antigen (PSA)

Stacy Loeb, Sara N. Gashti, William J Catalona*

*Corresponding author for this work

Research output: Contribution to journalReview article

33 Scopus citations

Abstract

Prostate inflammation can lead to an elevation in the serum PSA concentration and confound the use of PSA kinetics. This can have considerable clinical consequences, since these measurements form the basis for important clinical decisions. Thus, there has been investigation into ways to decrease the confounding from inflammation, including repeat PSA measurements after a period of observation or a course of empiric antibiotics. This article reviews the evidence about elevations in PSA due to prostatitis and describes the controversy over the optimal approach to reduce its confounding impact on prostate cancer screening.

Original languageEnglish (US)
Pages (from-to)64-66
Number of pages3
JournalUrologic Oncology: Seminars and Original Investigations
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2009

Keywords

  • Antibiotics
  • Prostate biopsy
  • Prostate cancer
  • Prostatitis
  • PSA

ASJC Scopus subject areas

  • Oncology
  • Urology

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