TY - CHAP
T1 - Executive functions
AU - Cristofori, Irene
AU - Cohen-Zimerman, Shira
AU - Grafman, Jordan
N1 - Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019
Y1 - 2019
N2 - Executive functions (EFs) include high-order cognitive abilities such as working memory, inhibitory control, cognitive flexibility, planning, reasoning, and problem solving. EFs enable humans to achieve goals, adapt to novel everyday life situations, and manage social interactions. Traditionally EFs have been associated with frontal lobe functioning. More recent evidence shows that posterior and subcortical regions also play a crucial role in EF processing, especially in the integration of sensory information and emotion. This chapter reviews the variety of EFs and their neural underpinning, based on lesion mapping and neuroimaging studies, as well as the evidence for rehabilitation interventions, neuropsychological assessment based on standard and ecologically valid tests, development, and genetic predisposition for recovery of executive functions after brain injury. Taken together, the EFs are critical for unique human abilities and more careful analyses of their subcomponents may help the development of targeted translational interventions to improve them.
AB - Executive functions (EFs) include high-order cognitive abilities such as working memory, inhibitory control, cognitive flexibility, planning, reasoning, and problem solving. EFs enable humans to achieve goals, adapt to novel everyday life situations, and manage social interactions. Traditionally EFs have been associated with frontal lobe functioning. More recent evidence shows that posterior and subcortical regions also play a crucial role in EF processing, especially in the integration of sensory information and emotion. This chapter reviews the variety of EFs and their neural underpinning, based on lesion mapping and neuroimaging studies, as well as the evidence for rehabilitation interventions, neuropsychological assessment based on standard and ecologically valid tests, development, and genetic predisposition for recovery of executive functions after brain injury. Taken together, the EFs are critical for unique human abilities and more careful analyses of their subcomponents may help the development of targeted translational interventions to improve them.
KW - Executive functions (EFs)
KW - development
KW - genetics
KW - lesion mapping studies
KW - neuroimaging
KW - neuropsychological assessment
KW - training and remediation
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U2 - 10.1016/B978-0-12-804281-6.00011-2
DO - 10.1016/B978-0-12-804281-6.00011-2
M3 - Chapter
C2 - 31590731
AN - SCOPUS:85072792172
T3 - Handbook of Clinical Neurology
SP - 197
EP - 219
BT - Handbook of Clinical Neurology
PB - Elsevier B.V.
ER -