Expanding the bioheat equation to include tissue internal water evaporation during heating

Deshan Yang, Mark C. Converse*, David M. Mahvi, John G. Webster

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

217 Scopus citations

Abstract

We propose a new method to study high temperature tissue ablation using an expanded bioheat diffusion equation. An extra term added to the bioheat equation is combined with the specific heat into an effective (temperature dependent) specific heat. It replaces the normal specific heat term in the modified bioheat equation, which can then be used at temperatures where water evaporation is expected to occur. This new equation is used to numerically simulate the microwave ablation of bovine liver and is compared to experimental ex vivo results.

Original languageEnglish (US)
Pages (from-to)1382-1388
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Volume54
Issue number8
DOIs
StatePublished - Aug 2007

Funding

Manuscript received November 15, 2005; revised November 8, 2006. This work was supported in part by the National Institutes of Health (NIH) under Grant DK58839. Asterisk indicates corresponding author. D. Yang is with the Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706 USA. *M. C. Converse is with the Department of Surgery, University of Wisconsin, 2151 Engineering Centers Building, 1550 Engineering Dr, Madison, WI 53706 USA. (e-mail: [email protected]). D. M. Mahvi is with the Department of Surgery, University of Wisconsin, Madison, WI 53792 USA. J. G. Webster is with the Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706 USA. Digital Object Identifier 10.1109/TBME.2007.890740

Keywords

  • Ablation
  • Bioheat equation
  • Liver
  • Microwave
  • Specific heat

ASJC Scopus subject areas

  • Biomedical Engineering

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