Exploiting the Curtin - Hammett Principle - Recognition-Mediated Acceleration of an Aldol Reaction

Sarah J. Howell; Peter R. Ashton; Neil Spencer; Douglas Philp

doi:10.1021/ol006821q

Exploiting the Curtin - Hammett Principle - Recognition-Mediated Acceleration of an Aldol Reaction

Sarah J. Howell, Peter R. Ashton, Neil Spencer, Douglas Philp^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

(Matrix Presented) Curtin-Hammett-Winstein-Holness kinetics are exploited in the acceleration of the aldol reaction between formylbenzo-15-crown-5 and acetylbenzo-15-crown-5. Potassium cations facilitate this acceleration through the fast, reversible formation of a 1:1:1 sandwich complex between the crown ethers and the metal cation.

Original language	English (US)
Pages (from-to)	353-356
Number of pages	4
Journal	Organic Letters
Volume	3
Issue number	3
DOIs	https://doi.org/10.1021/ol006821q
State	Published - Feb 8 2001

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1021/ol006821q

Cite this

@article{1e818e80e95843c0874aaf7f5d2a7f50,

title = "Exploiting the Curtin - Hammett Principle - Recognition-Mediated Acceleration of an Aldol Reaction",

abstract = "(Matrix Presented) Curtin-Hammett-Winstein-Holness kinetics are exploited in the acceleration of the aldol reaction between formylbenzo-15-crown-5 and acetylbenzo-15-crown-5. Potassium cations facilitate this acceleration through the fast, reversible formation of a 1:1:1 sandwich complex between the crown ethers and the metal cation.",

author = "Howell, {Sarah J.} and Ashton, {Peter R.} and Neil Spencer and Douglas Philp",

year = "2001",

month = feb,

day = "8",

doi = "10.1021/ol006821q",

language = "English (US)",

volume = "3",

pages = "353--356",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - Exploiting the Curtin - Hammett Principle - Recognition-Mediated Acceleration of an Aldol Reaction

AU - Howell, Sarah J.

AU - Ashton, Peter R.

AU - Spencer, Neil

AU - Philp, Douglas

PY - 2001/2/8

Y1 - 2001/2/8

N2 - (Matrix Presented) Curtin-Hammett-Winstein-Holness kinetics are exploited in the acceleration of the aldol reaction between formylbenzo-15-crown-5 and acetylbenzo-15-crown-5. Potassium cations facilitate this acceleration through the fast, reversible formation of a 1:1:1 sandwich complex between the crown ethers and the metal cation.

AB - (Matrix Presented) Curtin-Hammett-Winstein-Holness kinetics are exploited in the acceleration of the aldol reaction between formylbenzo-15-crown-5 and acetylbenzo-15-crown-5. Potassium cations facilitate this acceleration through the fast, reversible formation of a 1:1:1 sandwich complex between the crown ethers and the metal cation.

UR - http://www.scopus.com/inward/record.url?scp=0442327201&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0442327201&partnerID=8YFLogxK

U2 - 10.1021/ol006821q

DO - 10.1021/ol006821q

M3 - Article

C2 - 11428012

AN - SCOPUS:0442327201

SN - 1523-7060

VL - 3

SP - 353

EP - 356

JO - Organic Letters

JF - Organic Letters

IS - 3

ER -

Exploiting the Curtin - Hammett Principle - Recognition-Mediated Acceleration of an Aldol Reaction

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this