Exploring new and existing PrEP modalities among female sex workers and women who inject drugs in a U.S. city

Katherine H.A. Footer*, Sahnah Lim, Christine Tagliaferri Rael, George J. Greene, Alex Carballa-Diéguez, Rebecca Giguere, Michelle Martinez, Walter Bockting, Richard D’Aquila, Susan G. Sherman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


To address a shortage in research on Pre-Exposure Prophylaxis (PrEP) amongst women at high risk of HIV acquisition, this study explored the attitudes and preferences of female sex workers (FSW) (n = 15) and women who inject drugs (WWID) (n = 16) to existing (e.g., pill) and new (e.g., injection, implant) PrEP modalities, in Baltimore, Maryland, U.S.A. This study reports on seven focus groups conducted between December 2016 and April 2017 and aims to provide new insights into FSW and WWID attitudes and preferences towards three different PrEP delivery methods (i.e., PrEP pill, PrEP implant, PrEP injection). Results draw upon the PrEP care continuum framework and distill existing factors, including lack of control over side effects with new, longer lasting modalities, better privacy with injections, increased adherence with reduced dosing schedules from longer lasting PrEP and new factors such as perceptibility concerns with respect to the PrEP implant relevant to PrEP uptake and adherence among two important overlapping, at-risk populations. The study contributes to a better understanding of barriers and facilitators to uptake and adherence for FSW and WWID around both existing and new PrEP modalities, with implications for future clinical trials and PrEP interventions with at risk-populations.

Original languageEnglish (US)
Pages (from-to)1207-1213
Number of pages7
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Issue number10
StatePublished - Oct 3 2019


  • HIV
  • Modes of delivery
  • PrEP
  • female injection drug user
  • female sex worker

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Social Psychology


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