Exposure to violence and cardiovascular and neuroendocrine measures in adolescents

Rama Murali, Edith Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

56 Scopus citations


Background: Exposure to violence has clear, detrimental psychological consequences, but the physiological effects are less well understood. Purpose: This study examined the influence of exposure to violence on biological basal and reactivity measures in adolescents. Methods: There were 115 high school student participants. Systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), HR variability (HRV), and cortisol levels were recorded during baseline and a laboratory stressor, The Exposure to Violence interview was administered and assessed two dimensions: total observed violence and total personally experienced violence. These were then divided into component parts: lifetime frequency, proximity, and severity. Results: Greater total experienced violence was associated with increased basal SBP (β = .19, p < .05) and decreased acute stress reactivity in terms of SBP (β = -.13, p = .05), HR (β = -.21, p = .00), and HRV (β = .13, p = .05). Lifetime frequency of experienced violence was associated with higher basal DBP (r = .33, p < .05), HR (r = .33, p < .05), and cortisol (r = .53, p < .00), and decreased SBP (β = -.27, p < .05) and DBP (β = -.31, p < .05) reactivity. Exposure to violence is associated with increased biological basal levels in adolescents, supporting allostatic-load research and decreased cardiovascular reactivity, supporting the inoculation effect. Conclusions: The findings illustrate that being a victim of violence has more pervasive biological consequences than witnessing violence and that the accumulation of stressful experiences has the greatest effect on biological markers.

Original languageEnglish (US)
Pages (from-to)155-163
Number of pages9
JournalAnnals of Behavioral Medicine
Issue number2
StatePublished - 2005

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health


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