Expression genetics: A different approach to cancer diagnosis and prognosis

Ming Zhang*, Katherine J. Martin, Shijie Sheng, Ruth Sager

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Expression genetics is a new approach to the identification of cancer-related genes. Instead of studying gene mutations at the genome level, it focuses on the investigation of heredity at the RNA level. By isolating genes whose expression is up or down regulated in cancers, expression geneticists study their function in the context of gene regulation. A major goal of expression genetics in cancer is to correct gene expression in tumors by the application of potential therapeutic agents.

Original languageEnglish (US)
Pages (from-to)66-71
Number of pages6
JournalTrends in Biotechnology
Issue number2
StatePublished - Feb 1 1998

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


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