Expression of potassium channels in gerbil outer hair cells during development does not require neural induction

David Z.Z. He*, Peter Dallos

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Mammalian outer hair cells (OHCs) contain Ca and K channels in their synaptic pole. We questioned if the ontogeny of potassium currents of OHCs depends on the neural induction of early afferent contact. By recording whole-cell currents of OHCs grown in organotypic cultures deprived of afferent innervation, we show that a Ca-activated K channel is expressed in these cells, suggesting that the ontogeny of the K channel is an intrinsic process.

Original languageEnglish (US)
Pages (from-to)95-97
Number of pages3
JournalDevelopmental Brain Research
Volume103
Issue number1
DOIs
StatePublished - Oct 20 1997

Keywords

  • Afferent innervation
  • Development
  • Gerbil
  • K channel
  • Neural induction
  • Neurotrophic factor
  • Outer hair cell

ASJC Scopus subject areas

  • Developmental Neuroscience
  • Developmental Biology

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