Extending the recognition site of designed minor groove binding molecules

B. H. Geierstanger, M. Mrksich, P. B. Dervan, D. E. Wemmer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1: 1/2 :1 mode.

Original languageEnglish (US)
Pages (from-to)321-324
Number of pages4
JournalNature Structural Biology
Volume3
Issue number4
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Genetics

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