Extending the recognition site of designed minor groove binding molecules

B. H. Geierstanger; M. Mrksich; P. B. Dervan; D. E. Wemmer

doi:10.1038/nsb0496-321

Extending the recognition site of designed minor groove binding molecules

B. H. Geierstanger, M. Mrksich, P. B. Dervan, D. E. Wemmer^*

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1: 1/2 :1 mode.

Original language	English (US)
Pages (from-to)	321-324
Number of pages	4
Journal	Nature Structural Biology
Volume	3
Issue number	4
DOIs	https://doi.org/10.1038/nsb0496-321
State	Published - Apr 1 1996

ASJC Scopus subject areas

Genetics
Structural Biology
Biochemistry

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title = "Extending the recognition site of designed minor groove binding molecules",

abstract = "A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1: 1/2 :1 mode.",

author = "Geierstanger, {B. H.} and M. Mrksich and Dervan, {P. B.} and Wemmer, {D. E.}",

year = "1996",

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AU - Mrksich, M.

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N2 - A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1: 1/2 :1 mode.

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Extending the recognition site of designed minor groove binding molecules

Abstract

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