Extensively drug resistant tuberculosis in Mali: A case report

Bassirou Diarra*, Yacouba Toloba, Bakary Konate, Moumine Sanogo, Antieme Combo Georges Togo, Fatimata Camara, Gaoussou Berthe, Dianguina Soumaré, Bocar Baya, Drissa Goita, Yeya Dit Sadio Sarro, Mamoudou Maiga, Michael Belson, Susan Orsega, Sounkalo Dao, Robert L. Murphy, Sophia Siddiqui, Bouke C. De Jong, Seydou Doumbia, Souleymane Diallo

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Background: Drug resistant tuberculosis presents a major public health challenge. Case presentation: We present here the first two patients diagnosed with extensively drug resistant tuberculosis in Bamako, Mali. Genotypic findings suggest possible nosocomial transmission from the first patient to the second one, resulting in superinfection of the second patient. After being diagnosed with extensively drug resistant tuberculosis in August 2016, the patients only started receiving appropriate treatment 10 months later. Conclusion: The identification of these patients highlights the need for improved diagnostic and treatment algorithms for better surveillance and management of drug resistance in Mali. In the interest of these as well as future patients suffering from resistant tuberculosis, all steps recommended for programmatic management of drug resistant tuberculosis must be urgently prioritized in order to strengthen the multidrug resistant tuberculosis program.

Original languageEnglish (US)
Article number561
JournalBMC Research Notes
Volume10
Issue number1
DOIs
StatePublished - Nov 6 2017

Keywords

  • Bamako
  • Mali
  • Treatment
  • XDR-TB

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Diarra, B., Toloba, Y., Konate, B., Sanogo, M., Togo, A. C. G., Camara, F., Berthe, G., Soumaré, D., Baya, B., Goita, D., Sarro, Y. D. S., Maiga, M., Belson, M., Orsega, S., Dao, S., Murphy, R. L., Siddiqui, S., De Jong, B. C., Doumbia, S., & Diallo, S. (2017). Extensively drug resistant tuberculosis in Mali: A case report. BMC Research Notes, 10(1), [561]. https://doi.org/10.1186/s13104-017-2890-4