Extent of anesthesia and hemodynamic effects after subarachnoid administration of bupivacaine with epinephrine

A. A. Van Zundert, A. M. De Wolf

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

It has been suggested that the amount of local anesthetic injected into the subarachnoid space is more important than the volume or concentration that is used in determining the extent of anesthesia. However, this conclusion was based on studies using small volumes of local anesthetic (e.g., 1-4 ml). We have used larger volumes of local anesthetic (10 ml) for subarachnoid anesthesia, with good analgesia and without complications. We have now evaluated the effect of using widely disparate volumes (2.5 vs 10 ml) and concentrations (0.5% vs 0.125%) of bupivacaine while maintaining a cosntant dose (12.5 mg) on the extent of sensory anesthesia and the resultant hemodynamic changes.

Original languageEnglish (US)
Pages (from-to)784-787
Number of pages4
JournalAnesthesia and analgesia
Volume67
Issue number8
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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