New animal models are beginning to explain the neural circuits involved in the acquisition, consolidation, and retrieval of extinction. The majority of research on extinction has been based on the well-defined circuitry underlying Pavlovian conditioned fear, but many aspects of the fear extinction network are paralleled in the extinction of other aversive and appetitive behaviors. In this article, we review the neural anatomy underlying extinction and discuss the mechanisms that occur within and between structures to inhibit behavioral responses after extinction.
- Prefrontal cortex
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