Extracorporeal life support for status asthmaticus

M. B. Shapiro, A. C. Kleaveland, R. H. Bartlett*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Status asthmaticus is a life-threatening form of reactive airway disease, refractory to initial control with ordinary medical measures, sometimes requiring mechanical ventilatory assistance. In this report, we describe a patient whose bronchospasm could not be controlled with conventional measures, with severe respiratory acidosis (PaCO2 consistently >100 mm Hg), who was successfully supported with extracorporeal life support (ECLS). During ECLS, arterial blood gas values rapidly returned to normal, and bronchospasm resolved during the subsequent 24 h. The patient was extubated hours later, and discharged to home 4 days later, neurologically normal. We believe that this represents the first application of this technology to this disease in an adult patient.

Original languageEnglish (US)
Pages (from-to)1651-1654
Number of pages4
Issue number6
StatePublished - 1993

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine


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