Extrahepatic portal vein thrombosis is associated with an increased incidence of cholelithiasis

Bill Chiu, Riccardo Superina*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Background/Purpose The effect of portal flow deprivation to the liver on bile composition and the biliary system remains undefined in children. This report catalogues the authors' experience with biliary tract problems in children with extrahepatic portal vein thrombosis (EHPVT). Methods Twenty-nine children with symptomatic idiopathic EHPVT were evaluated for the Rex shunt procedure (mesenterico-left portal bypass) over a 4-year period. The authors retrospectively reviewed all operative reports and pre- and postoperative abdominal ultrasound findings with regard to associated congenital anomalies and abnormal biliary tract findings. Results Seven of the 29 patients with EHPVT (24%) had associated nonbiliary congenital abnormalities. Twenty-four of 29 (83%) patients had detectable biliary tract pathology by ultrasound examination. Biliary symptoms developed in 3 of the 9 (33%) patients with either stones or sludge (10.3% of all patients). Two patients were treated by cholecystectomy. There was no statistical correlation between biliary tract pathology and the age of presentation, symptoms of portal hypertension, gender, or underlying medical condition. Conclusions The authors have noted a high incidence of biliary tract pathology in patients with EHPVT compared with the normal population and a 10% incidence of symptomatic biliary pathology in this series.

Original languageEnglish (US)
Pages (from-to)1059-1061
Number of pages3
JournalJournal of pediatric surgery
Issue number7
StatePublished - Jul 2004


  • Portal vein thrombosis
  • cholelithiasis

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Extrahepatic portal vein thrombosis is associated with an increased incidence of cholelithiasis'. Together they form a unique fingerprint.

Cite this