Eye manifestations of intrauterine infections

Marilyn Baird Mets*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


The eye finding most characteristic of a pre-natal, and therefore, congenital infection is a chorioretinal scar or an active chorioretinitis as can be seen in congenital toxoplasmosis, CMV, HSV, lymphocytic choriomeningitis virus, or varicella zoster infections. Congenital cataracts are suggestive, but less specific for congenital infection. They may be a relatively isolated finding in rubella, syphilis, varicella zoster, and Epstein-Barr virus infections. When they are present in congenital toxoplasmosis, HSV, and CMV, they are associated with extensive eye involvement. Other manifestations are less common as discussed above. The mechanism of action of these agents appears to be both a direct toxic and a teratogenic effect.

Original languageEnglish (US)
Pages (from-to)521-531
Number of pages11
JournalOphthalmology Clinics of North America
Issue number3
StatePublished - 2001

ASJC Scopus subject areas

  • Ophthalmology


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