Eye movements in amyotrophic lateral sclerosis and its mimics: A review with illustrative cases

Colette Donaghy*, Matthew J. Thurtell, Erik P. Pioro, J. Mark Gibson, R. John Leigh

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations

Abstract

Abnormal eye movements are increasingly recognised in patients with amyotrophic lateral sclerosis (ALS) and, when they occur, may provide insights into the pattern and pathogenesis of the disease process. In patients with disorders that mimic ALS, abnormal eye movements may point to the correct diagnosis. In both of these circumstances, systematic examination of eye movements and interpretation of the findings with reference to modern concepts of their neural substrate will aid diagnosis and suggest pathogenesis. Here, key points with illustrative case histories and eye movement records are highlighted.

Original languageEnglish (US)
Pages (from-to)110-116
Number of pages7
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume82
Issue number1
DOIs
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

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