Fabricating customized hydrogel contact lens

Andre Childs, Hao Li, Daniella M. Lewittes, Biqin Dong, Wenzhong Liu, Xiao Shu, Cheng Sun, Hao F. Zhang*

*Corresponding author for this work

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Contact lenses are increasingly used in laboratories for in vivo animal retinal imaging and pre-clinical studies. The lens shapes often need modification to optimally fit corneas of individual test subjects. However, the choices from commercially available contact lenses are rather limited. Here, we report a flexible method to fabricate customized hydrogel contact lenses. We showed that the fabricated hydrogel is highly transparent, with refractive indices ranging from 1.42 to 1.45 in the spectra range from 400 nm to 800 nm. The Young's modulus (1.47 MPa) and hydrophobicity (with a sessile drop contact angle of 40.5°) have also been characterized experimentally. Retinal imaging using optical coherence tomography in rats wearing our customized contact lenses has the quality comparable to the control case without the contact lens. Our method could significantly reduce the cost and the lead time for fabricating soft contact lenses with customized shapes, and benefit the laboratorial-used contact lenses in pre-clinical studies.

Original languageEnglish (US)
Article number34905
JournalScientific reports
Volume6
DOIs
StatePublished - Oct 17 2016

ASJC Scopus subject areas

  • General

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    Childs, A., Li, H., Lewittes, D. M., Dong, B., Liu, W., Shu, X., Sun, C., & Zhang, H. F. (2016). Fabricating customized hydrogel contact lens. Scientific reports, 6, [34905]. https://doi.org/10.1038/srep34905