Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

Henry Oliver T. Ware; Adam C. Farsheed; Evan Baker; Guillermo Ameer; Cheng Sun

doi:10.1016/j.procir.2017.04.038

Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

Henry Oliver T. Ware, Adam C. Farsheed, Evan Baker, Guillermo Ameer, Cheng Sun^*

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

7 Scopus citations

Abstract

The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

Original language	English (US)
Pages (from-to)	131-138
Number of pages	8
Journal	Procedia CIRP
Volume	65
DOIs	https://doi.org/10.1016/j.procir.2017.04.038
State	Published - 2017
Event	3rd CIRP Conference on BioManufacturing 2017 - Chicago, United States Duration: Jul 11 2017 → Jul 14 2017

Keywords

3D Printing
Bioresorbable Vascular Scaffold
μCLIP

ASJC Scopus subject areas

Control and Systems Engineering
Industrial and Manufacturing Engineering

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@article{30bccde6a2404e90a43c6527bb2f1de9,

title = "Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds",

abstract = "The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.",

keywords = "3D Printing, Bioresorbable Vascular Scaffold, μCLIP",

author = "Ware, {Henry Oliver T.} and Farsheed, {Adam C.} and Evan Baker and Guillermo Ameer and Cheng Sun",

note = "Funding Information: Henry Oliver T. Ware would like to acknowledge the National Science Foundation Graduate Research Program as he is a recipient of the fellowship.; 3rd CIRP Conference on BioManufacturing 2017 ; Conference date: 11-07-2017 Through 14-07-2017",

year = "2017",

doi = "10.1016/j.procir.2017.04.038",

language = "English (US)",

volume = "65",

pages = "131--138",

journal = "Procedia CIRP",

issn = "2212-8271",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

AU - Ware, Henry Oliver T.

AU - Farsheed, Adam C.

AU - Baker, Evan

AU - Ameer, Guillermo

AU - Sun, Cheng

N1 - Funding Information: Henry Oliver T. Ware would like to acknowledge the National Science Foundation Graduate Research Program as he is a recipient of the fellowship.

PY - 2017

Y1 - 2017

N2 - The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

AB - The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

KW - 3D Printing

KW - Bioresorbable Vascular Scaffold

KW - μCLIP

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JF - Procedia CIRP

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