Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

Henry Oliver T. Ware; Adam C. Farsheed; Evan Baker; Guillermo Ameer; Cheng Sun

doi:10.1016/j.procir.2017.04.038

Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

Henry Oliver T. Ware, Adam C. Farsheed, Evan Baker, Guillermo Ameer, Cheng Sun^*

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

17 Scopus citations

Abstract

The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

Original language	English (US)
Pages (from-to)	131-138
Number of pages	8
Journal	Procedia CIRP
Volume	65
DOIs	https://doi.org/10.1016/j.procir.2017.04.038
State	Published - 2017
Event	3rd CIRP Conference on BioManufacturing 2017 - Chicago, United States Duration: Jul 11 2017 → Jul 14 2017

Funding

Henry Oliver T. Ware would like to acknowledge the National Science Foundation Graduate Research Program as he is a recipient of the fellowship.

Keywords

3D Printing
Bioresorbable Vascular Scaffold
μCLIP

ASJC Scopus subject areas

Control and Systems Engineering
Industrial and Manufacturing Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.procir.2017.04.038

Cite this

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title = "Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds",

abstract = "The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.",

keywords = "3D Printing, Bioresorbable Vascular Scaffold, μCLIP",

author = "Ware, \{Henry Oliver T.\} and Farsheed, \{Adam C.\} and Evan Baker and Guillermo Ameer and Cheng Sun",

note = "Publisher Copyright: {\textcopyright} 2016 Published by Elsevier B.V.; 3rd CIRP Conference on BioManufacturing 2017 ; Conference date: 11-07-2017 Through 14-07-2017",

year = "2017",

doi = "10.1016/j.procir.2017.04.038",

language = "English (US)",

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journal = "Procedia CIRP",

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AU - Ware, Henry Oliver T.

AU - Farsheed, Adam C.

AU - Baker, Evan

AU - Ameer, Guillermo

AU - Sun, Cheng

PY - 2017

Y1 - 2017

N2 - The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

AB - The recent development of Continuous Liquid Interface Production, also known as CLIP, has successfully alleviated the main obstacles surrounding 3D printing technologies: production speed and part quality. Based on this technology, we developed the μCLIP process to allow for 3D printing of biomedical devices with micron-scale precision. In this study, we report the process development in manufacturing high-resolution bioresorbable scaffolds using our own μCLIP system and a bioresorbable photopolymerizable biomaterial (B-Ink). Through optimization of our μCLIP process and concentration of B-Ink components, we have reduced the fabrication time of a customizable BVSs from several hours to 11.25 minutes. Optimized ink was shown to possess mechanical stiffness comparable to a nitinol control stent.

KW - 3D Printing

KW - Bioresorbable Vascular Scaffold

KW - μCLIP

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Fabrication Speed Optimization for High-resolution 3D-printing of Bioresorbable Vascular Scaffolds

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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