Factors affecting the risk of blood bank specimen hemolysis

Paula Tanabe; Demetrious N. Kyriacou; Franklyn Garland

doi:10.1197/aemj.10.8.897

Factors affecting the risk of blood bank specimen hemolysis

Paula Tanabe^*, Demetrious N. Kyriacou, Franklyn Garland

^*Corresponding author for this work

Emergency Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Objectives: To evaluate simultaneously several possible risk factors for blood bank specimen hemolysis. Methods: This was a prospective cohort study of emergency department and labor and delivery patients to estimate the effect of various factors on the risk of blood bank specimen hemolysis. Study variables included patient demographics, type and gauge of needle or catheter, anatomic location of venipuncture, and patient care area. Hemolysis was determined by blood bank laboratory technicians. Cox proportional hazards multivariate regression modeling was performed to estimate the adjusted relative risks for hemolysis. Results: Of the 605 subjects with complete data, 194 (32.1%) subjects had blood-specimens drawn directly with a steel needle, and 411 (69.1%) had specimens drawn through a Vialon (BD Medical Systems, Inc., Sandy, UT) intravenous (IV) angiocatheter. The overall risk of hemolysis for all was 7%, 10% for Vialon IV angiocatheters and 1.5% for steel needles. In the multivariate analysis, the factors most closely associated with hemolysis were the use of Vialon IV catheters and sampling from an anatomic site other than the antecubital area. Conclusions: Blood bank specimens drawn from Vialon IV catheters (particularly smaller gauge catheters) and from veins outside the antecubital area are at significantly increased risk to hemolyze.

Original language	English (US)
Pages (from-to)	897-900
Number of pages	4
Journal	Academic Emergency Medicine
Volume	10
Issue number	8
DOIs	https://doi.org/10.1197/aemj.10.8.897
State	Published - Aug 1 2003

Funding

Supported by an Excellence in Academic Medicine grant from the State of Illinois and Northwestern Memorial Hospital and endowed fund donated by Abra Prentice Wilkin to emergency medicine. Dr. Tanabe is currently supported as a Ruth L. Kirschstein National Research Service Award postdoctoral fellow at the Institute for Health Services Research and Policy Studies of Northwestern University's Feinberg School of Medicine under an institutional award from the Agency for Healthcare Research and Quality. None of the authors have any relationships with any companies that would compromise the integrity of the project.

Keywords

Blood-bank
Hemolysis
Intravenous (IV) catheters
Specimen

ASJC Scopus subject areas

Emergency Medicine

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10.1197/aemj.10.8.897

Cite this

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title = "Factors affecting the risk of blood bank specimen hemolysis",

abstract = "Objectives: To evaluate simultaneously several possible risk factors for blood bank specimen hemolysis. Methods: This was a prospective cohort study of emergency department and labor and delivery patients to estimate the effect of various factors on the risk of blood bank specimen hemolysis. Study variables included patient demographics, type and gauge of needle or catheter, anatomic location of venipuncture, and patient care area. Hemolysis was determined by blood bank laboratory technicians. Cox proportional hazards multivariate regression modeling was performed to estimate the adjusted relative risks for hemolysis. Results: Of the 605 subjects with complete data, 194 (32.1%) subjects had blood-specimens drawn directly with a steel needle, and 411 (69.1%) had specimens drawn through a Vialon (BD Medical Systems, Inc., Sandy, UT) intravenous (IV) angiocatheter. The overall risk of hemolysis for all was 7%, 10% for Vialon IV angiocatheters and 1.5% for steel needles. In the multivariate analysis, the factors most closely associated with hemolysis were the use of Vialon IV catheters and sampling from an anatomic site other than the antecubital area. Conclusions: Blood bank specimens drawn from Vialon IV catheters (particularly smaller gauge catheters) and from veins outside the antecubital area are at significantly increased risk to hemolyze.",

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author = "Paula Tanabe and Kyriacou, {Demetrious N.} and Franklyn Garland",

note = "Funding Information: Supported by an Excellence in Academic Medicine grant from the State of Illinois and Northwestern Memorial Hospital and endowed fund donated by Abra Prentice Wilkin to emergency medicine. Dr. Tanabe is currently supported as a Ruth L. Kirschstein National Research Service Award postdoctoral fellow at the Institute for Health Services Research and Policy Studies of Northwestern University's Feinberg School of Medicine under an institutional award from the Agency for Healthcare Research and Quality. None of the authors have any relationships with any companies that would compromise the integrity of the project. ",

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N2 - Objectives: To evaluate simultaneously several possible risk factors for blood bank specimen hemolysis. Methods: This was a prospective cohort study of emergency department and labor and delivery patients to estimate the effect of various factors on the risk of blood bank specimen hemolysis. Study variables included patient demographics, type and gauge of needle or catheter, anatomic location of venipuncture, and patient care area. Hemolysis was determined by blood bank laboratory technicians. Cox proportional hazards multivariate regression modeling was performed to estimate the adjusted relative risks for hemolysis. Results: Of the 605 subjects with complete data, 194 (32.1%) subjects had blood-specimens drawn directly with a steel needle, and 411 (69.1%) had specimens drawn through a Vialon (BD Medical Systems, Inc., Sandy, UT) intravenous (IV) angiocatheter. The overall risk of hemolysis for all was 7%, 10% for Vialon IV angiocatheters and 1.5% for steel needles. In the multivariate analysis, the factors most closely associated with hemolysis were the use of Vialon IV catheters and sampling from an anatomic site other than the antecubital area. Conclusions: Blood bank specimens drawn from Vialon IV catheters (particularly smaller gauge catheters) and from veins outside the antecubital area are at significantly increased risk to hemolyze.

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Factors affecting the risk of blood bank specimen hemolysis

Abstract

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Keywords

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