Factors associated with early in vitro fertilization treatment discontinuation

Bronwyn S. Bedrick, Kelsey Anderson, Darcy E. Broughton, Barton Hamilton, Emily S. Jungheim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Objective: To investigate factors associated with early IVF treatment discontinuation. Design: Retrospective cohort study. Setting: Academic medical center. Patient(s): Six hundred sixty-nine first-attempt IVF patients who did not have a live birth. Intervention(s): None. Main Outcome Measure(s): Treatment discontinuation and time to return for a second IVF cycle. Result(s): Women without IVF insurance coverage were more likely to discontinue treatment than women with insurance coverage (adjusted odds ratio [aOR] = 3.12; 95% confidence interval [CI], 2.22–4.40). African-American women were more likely to discontinue treatment (aOR = 2.95; 95% CI, 1.54–5.66) and returned for treatment more slowly (adjusted hazard ratio [aHR] = 0.44; 95% CI, 0.28–0.71) than non-Hispanic white women, regardless of IVF insurance coverage or income. Women with a poor prognosis were more likely to discontinue treatment than women with a good prognosis. Older women with IVF insurance coverage or a good prognosis had a shorter time to return for a second IVF cycle than older women without IVF insurance coverage or with a poor prognosis. Estimated income, distance to clinic, fertility diagnosis, number of oocytes retrieved, and history of previous live birth were not associated with treatment discontinuation or time to return for a second IVF cycle after adjustment for covariates. Conclusion(s): IVF insurance coverage, race, age, and future treatment prognosis are associated with IVF treatment discontinuation and time to return.

Original languageEnglish (US)
Pages (from-to)105-111
Number of pages7
JournalFertility and Sterility
Volume112
Issue number1
DOIs
StatePublished - Jul 2019
Externally publishedYes

Keywords

  • IVF
  • IVF insurance
  • access to care
  • disparity
  • treatment termination

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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