Fatal cardiovascular collapse due to BK virus infection of capillary endothelial cells in a renal transplant recipient: A novel clinical syndrome

George Sakoulas*, Igor J. Koralnik, David Shaffer, Martha Pavlakis

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

BK virus (BKV) is an increasingly recognized cause of acute renal allograft dysfunction. The most common manifestations of BKV infection in renal transplant patients include asymptomatic viral shedding in the urine, renal allograft dysfunction, and ureteral stenosis. This is the first report of BKV infection causing systemic endothelial cell injury with capillary leak, cardiovascular collapse, multiorgan failure, and death. The authors alert clinicians to this as a possible emerging infection in the setting of more potent immunosuppression regimens among renal transplant patients.

Original languageEnglish (US)
Pages (from-to)S104-S110
JournalGraft
Volume5
Issue numberSUPPL.
DOIs
StatePublished - Dec 2002

ASJC Scopus subject areas

  • Transplantation

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