Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis

P. Carolis; M. Galeotti; G. Ficarra; M. Masetti; D. Grimaldi; P. Cortelli

doi:10.1007/s10072-006-0709-5

Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis

P. Carolis, M. Galeotti, G. Ficarra, M. Masetti, D. Grimaldi, P. Cortelli

Neurology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.

Original language	English (US)
Pages (from-to)	352-354
Number of pages	3
Journal	Neurological Sciences
Volume	27
Issue number	5
DOIs	https://doi.org/10.1007/s10072-006-0709-5
State	Published - Nov 2006

Keywords

Cerebral haemorrhage
Liver transplantation
Transthyretin amyloidosis

ASJC Scopus subject areas

Clinical Neurology
Psychiatry and Mental health
Dermatology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10072-006-0709-5

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abstract = "Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.",

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T1 - Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis

AU - Carolis, P.

AU - Galeotti, M.

AU - Ficarra, G.

AU - Masetti, M.

AU - Grimaldi, D.

AU - Cortelli, P.

PY - 2006/11

Y1 - 2006/11

N2 - Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.

AB - Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.

KW - Cerebral haemorrhage

KW - Liver transplantation

KW - Transthyretin amyloidosis

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Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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