Fatal pneumococcal infections following allogeneic bone marrow transplant

K. Rege, J. Mehta, J. Treleaven*, B. Jameson, S. T. Meller, P. Mitchell, S. Milan, R. L. Powles

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Six cases of fatal pneumococcal sepsis are described, occurring in the post-allograft setting, between 3 and 39 months after transplantation. Five of the six patients were suffering from chronic graft-versus-host disease and were receiving immunosuppressive therapy. Most were receiving prophylactic antibiotic therapy. This represents approximately 2% of the allograft population treated during the study period who survived for > 3 months after transplant. Pneumococcal sepsis is thus still a significant cause of death after allogeneic BMT and approaches to minimise its occurrence are discussed.

Original languageEnglish (US)
Pages (from-to)903-906
Number of pages4
JournalBone Marrow Transplantation
Issue number6
StatePublished - Dec 1 1994

ASJC Scopus subject areas

  • Hematology
  • Transplantation


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