Feasibility, acceptability, and preliminary efficacy of a technology-assisted psychosocial intervention for racially diverse men with advanced prostate cancer

Betina R Yanez, Heather L. McGinty, David C Mohr, Mark J. Begale, Jason R. Dahn, Sarah C Flury, Kent T Perry Jr, Frank J Penedo*

*Corresponding author for this work

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

BACKGROUND The utility of psychosocial interventions in reducing symptom burden and improving health-related quality of life (HRQOL) for men with localized prostate cancer has been demonstrated. However, studies have yet to demonstrate the efficacy of interventions in advanced prostate cancer (APC). This study examined the feasibility, acceptability, and preliminary efficacy of a technology-assisted, 10-week, group-based psychosocial intervention for diverse men with APC. METHODS The participants were 74 men (mean age, 68.84 years; non-Hispanic white, 57%; black, 40.5%) who were randomized to a cognitive-behavioral stress management (CBSM) treatment or health promotion (HP) attention-control condition. The participants were assessed at the baseline, weekly throughout the 10-week program, and 6 months after the baseline. Outcomes were assessed with the Patient-Reported Outcomes Measurement Information System along with established measures of HRQOL, CBSM intervention targets (eg, relaxation skills), and patient-reported acceptability. RESULTS Feasibility was demonstrated through good retention rates (>85%) and acceptable average attendance rates (>70%), and acceptability was demonstrated through very favorable weekly session evaluations (mean score, 4/5) and exit surveys (mean score, 3.6/4). Men randomized to the CBSM condition reported significant reductions (P <.05) in depressive symptoms and improvements in relaxation self-efficacy (P <.05) at the 6-month follow-up. CBSM participants reported trends for improvement in distress and functional well-being (P <.08) in comparison with those in the HP condition. Effect sizes ranged from medium (0.54) to large (1.87) and, in some instances, were clinically meaningful. CONCLUSIONS Technology-based CBSM interventions among diverse men with APC may be feasible, acceptable, and efficacious. Cancer 2015;121:4407-15.

Original languageEnglish (US)
Pages (from-to)4407-4415
Number of pages9
JournalCancer
Volume121
Issue number24
DOIs
StatePublished - Dec 15 2015

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Prostatic Neoplasms
Technology
Health Promotion
Quality of Life
Feasibility Studies
Self Efficacy
Information Systems
Depression
Neoplasms
Therapeutics

Keywords

  • eHealth
  • prostate cancer
  • psychosocial aspects
  • quality of life
  • randomized trial

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

@article{0b963037274a41f49ae046cd7f3b3bf2,
title = "Feasibility, acceptability, and preliminary efficacy of a technology-assisted psychosocial intervention for racially diverse men with advanced prostate cancer",
abstract = "BACKGROUND The utility of psychosocial interventions in reducing symptom burden and improving health-related quality of life (HRQOL) for men with localized prostate cancer has been demonstrated. However, studies have yet to demonstrate the efficacy of interventions in advanced prostate cancer (APC). This study examined the feasibility, acceptability, and preliminary efficacy of a technology-assisted, 10-week, group-based psychosocial intervention for diverse men with APC. METHODS The participants were 74 men (mean age, 68.84 years; non-Hispanic white, 57{\%}; black, 40.5{\%}) who were randomized to a cognitive-behavioral stress management (CBSM) treatment or health promotion (HP) attention-control condition. The participants were assessed at the baseline, weekly throughout the 10-week program, and 6 months after the baseline. Outcomes were assessed with the Patient-Reported Outcomes Measurement Information System along with established measures of HRQOL, CBSM intervention targets (eg, relaxation skills), and patient-reported acceptability. RESULTS Feasibility was demonstrated through good retention rates (>85{\%}) and acceptable average attendance rates (>70{\%}), and acceptability was demonstrated through very favorable weekly session evaluations (mean score, 4/5) and exit surveys (mean score, 3.6/4). Men randomized to the CBSM condition reported significant reductions (P <.05) in depressive symptoms and improvements in relaxation self-efficacy (P <.05) at the 6-month follow-up. CBSM participants reported trends for improvement in distress and functional well-being (P <.08) in comparison with those in the HP condition. Effect sizes ranged from medium (0.54) to large (1.87) and, in some instances, were clinically meaningful. CONCLUSIONS Technology-based CBSM interventions among diverse men with APC may be feasible, acceptable, and efficacious. Cancer 2015;121:4407-15.",
keywords = "eHealth, prostate cancer, psychosocial aspects, quality of life, randomized trial",
author = "Yanez, {Betina R} and McGinty, {Heather L.} and Mohr, {David C} and Begale, {Mark J.} and Dahn, {Jason R.} and Flury, {Sarah C} and {Perry Jr}, {Kent T} and Penedo, {Frank J}",
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Feasibility, acceptability, and preliminary efficacy of a technology-assisted psychosocial intervention for racially diverse men with advanced prostate cancer. / Yanez, Betina R; McGinty, Heather L.; Mohr, David C; Begale, Mark J.; Dahn, Jason R.; Flury, Sarah C; Perry Jr, Kent T; Penedo, Frank J.

In: Cancer, Vol. 121, No. 24, 15.12.2015, p. 4407-4415.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Feasibility, acceptability, and preliminary efficacy of a technology-assisted psychosocial intervention for racially diverse men with advanced prostate cancer

AU - Yanez, Betina R

AU - McGinty, Heather L.

AU - Mohr, David C

AU - Begale, Mark J.

AU - Dahn, Jason R.

AU - Flury, Sarah C

AU - Perry Jr, Kent T

AU - Penedo, Frank J

PY - 2015/12/15

Y1 - 2015/12/15

N2 - BACKGROUND The utility of psychosocial interventions in reducing symptom burden and improving health-related quality of life (HRQOL) for men with localized prostate cancer has been demonstrated. However, studies have yet to demonstrate the efficacy of interventions in advanced prostate cancer (APC). This study examined the feasibility, acceptability, and preliminary efficacy of a technology-assisted, 10-week, group-based psychosocial intervention for diverse men with APC. METHODS The participants were 74 men (mean age, 68.84 years; non-Hispanic white, 57%; black, 40.5%) who were randomized to a cognitive-behavioral stress management (CBSM) treatment or health promotion (HP) attention-control condition. The participants were assessed at the baseline, weekly throughout the 10-week program, and 6 months after the baseline. Outcomes were assessed with the Patient-Reported Outcomes Measurement Information System along with established measures of HRQOL, CBSM intervention targets (eg, relaxation skills), and patient-reported acceptability. RESULTS Feasibility was demonstrated through good retention rates (>85%) and acceptable average attendance rates (>70%), and acceptability was demonstrated through very favorable weekly session evaluations (mean score, 4/5) and exit surveys (mean score, 3.6/4). Men randomized to the CBSM condition reported significant reductions (P <.05) in depressive symptoms and improvements in relaxation self-efficacy (P <.05) at the 6-month follow-up. CBSM participants reported trends for improvement in distress and functional well-being (P <.08) in comparison with those in the HP condition. Effect sizes ranged from medium (0.54) to large (1.87) and, in some instances, were clinically meaningful. CONCLUSIONS Technology-based CBSM interventions among diverse men with APC may be feasible, acceptable, and efficacious. Cancer 2015;121:4407-15.

AB - BACKGROUND The utility of psychosocial interventions in reducing symptom burden and improving health-related quality of life (HRQOL) for men with localized prostate cancer has been demonstrated. However, studies have yet to demonstrate the efficacy of interventions in advanced prostate cancer (APC). This study examined the feasibility, acceptability, and preliminary efficacy of a technology-assisted, 10-week, group-based psychosocial intervention for diverse men with APC. METHODS The participants were 74 men (mean age, 68.84 years; non-Hispanic white, 57%; black, 40.5%) who were randomized to a cognitive-behavioral stress management (CBSM) treatment or health promotion (HP) attention-control condition. The participants were assessed at the baseline, weekly throughout the 10-week program, and 6 months after the baseline. Outcomes were assessed with the Patient-Reported Outcomes Measurement Information System along with established measures of HRQOL, CBSM intervention targets (eg, relaxation skills), and patient-reported acceptability. RESULTS Feasibility was demonstrated through good retention rates (>85%) and acceptable average attendance rates (>70%), and acceptability was demonstrated through very favorable weekly session evaluations (mean score, 4/5) and exit surveys (mean score, 3.6/4). Men randomized to the CBSM condition reported significant reductions (P <.05) in depressive symptoms and improvements in relaxation self-efficacy (P <.05) at the 6-month follow-up. CBSM participants reported trends for improvement in distress and functional well-being (P <.08) in comparison with those in the HP condition. Effect sizes ranged from medium (0.54) to large (1.87) and, in some instances, were clinically meaningful. CONCLUSIONS Technology-based CBSM interventions among diverse men with APC may be feasible, acceptable, and efficacious. Cancer 2015;121:4407-15.

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