Abstract
Myocardial conduction velocity is important for the genesis of arrhythmias. In the normal heart, conduction is primarily dependent on fiber direction (anisotropy) and may be discontinuous at sites with tissue heterogeneities (trabeculated or fibrotic tissue). We present a semi-automated method for the accurate measurement of conduction velocity based on high-resolution activation mapping following central stimulation. The method was applied to activation maps created from myocardium from man, sheep and mouse with anisotropic and discontinuous conduction. Advantages of the presented method over existing methods are discussed.
Original language | English (US) |
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Pages (from-to) | 177-183 |
Number of pages | 7 |
Journal | Computers in Biology and Medicine |
Volume | 65 |
DOIs | |
State | Published - Oct 1 2015 |
Keywords
- Arrhythmia
- Conduction velocity
- Electrophysiology
- Fibrosis
- Optical mapping
ASJC Scopus subject areas
- Health Informatics
- Computer Science Applications