Fertility and Breast Cancer

Carlos A. Vieira*, Susan Folsom, Nora M. Hansen, Teresa K. Woodruff

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: Breast cancer is the most common malignancy diagnosed in women worldwide. As the average age of child-bearing increases, more women will not have started or completed their families at the time of a breast cancer diagnosis. The scope of this review is to present current practices for fertility preservation, evidence for such practices, and future directions for fertility counseling and treatment for women with breast cancer. Recent Findings: In the face of multimodality treatment for breast cancer including surgery, gonadotoxic chemotherapies, and radiation, women who desire to become biological mothers face complex decisions, including the pursuit of fertility preservation prior to treatment which may be dictated by age, ovarian reserve, and the choice of systemic therapy. Summary: Several considerations impact the decision to pursue fertility preservation, and practices are continually advancing. This discussion is aimed at improving access and information on fertility preservation methods in breast cancer patients.

Original languageEnglish (US)
Pages (from-to)72-80
Number of pages9
JournalCurrent Breast Cancer Reports
Volume13
Issue number2
DOIs
StatePublished - Jun 2021

Keywords

  • Breast cancer
  • Chemotoxicity
  • Fertility preservation
  • Gonadotoxicity
  • Oncofertility
  • Ovarian reserve

ASJC Scopus subject areas

  • Oncology

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