Fertility Preservation in Patients with Endometrioma

Jennifer Hirshfeld-Cytron*, Candace Tingen, Teresa K Woodruff

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The ultimate goals of endometriosis research are better diagnostics, especially for early stage and mild disease, and effective medical therapies that cure the disease. New candidate targets for diagnostics and therapeutics are most likely to be identified from fundamental research into the pathophysiology of endometriosis. Progress in these endeavors will depend on funding and the ability of researchers to maximize resources through collaboration and multidisciplinary approaches. Medical treatments undergoing investigation include progesterone and estrogen receptor modulators, statins, aromatase inhibitors, antiangiogenic agents, and immune modulators such as anti-tumor necrosis factor-α. None of these medical treatments is yet able to supplant surgical excision of endometriotic lesions as the gold standard for treatment. Despite the impediments to endometriosis research that include variable symptoms, multiple genetic and environmental causative influences and a lack of good experimental models, significant progress is being made in improving understanding of basic disease mechanisms, and in new approaches to diagnosis and treatment.

Original languageEnglish (US)
Title of host publicationEndometriosis
Subtitle of host publicationScience and Practice
PublisherWiley Blackwell
Pages555-559
Number of pages5
ISBN (Print)9781444332131
DOIs
StatePublished - Jan 25 2012

Keywords

  • Animal models
  • Diagnostics
  • Endometriosis
  • Future research
  • Genetic risk
  • Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Fertility Preservation in Patients with Endometrioma'. Together they form a unique fingerprint.

Cite this