Fetal diagnosis of KCNQ1-variant long QT syndrome using fetal echocardiography and magnetocardiography

Lajja Desai*, Ron Wakai, Sabrina Tsao, Janette Strasburger, Nina Gotteiner, Angira Patel

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

A pregnant woman with KCNQ1 variant long QT syndrome (LQTS) underwent fetal magnetocardiography (fMCG) after atrioventricular (AV) block was noted during fetal echocardiogram—atypical for LQTS type 1. Concern for fetal LQTS on fMCG prompted monitoring of maternal labs, change of maternal beta blocker therapy, and frequent fetal echocardiograms. Collaboration between obstetricians, neonatologists, and pediatric cardiologists ensured safe delivery. Beta blocker therapy was initiated after birth, and postnatal evaluation confirmed genotype and phenotype positive LQTS in the infant. Our experience suggests diagnosis and evaluation of fetal LQTS can alter antenatal management to reduce risk of poor fetal and postnatal outcomes.

Original languageEnglish (US)
Pages (from-to)430-433
Number of pages4
JournalPACE - Pacing and Clinical Electrophysiology
Volume43
Issue number4
DOIs
StatePublished - Apr 1 2020

Keywords

  • fetal bradycardia
  • fetal echocardiography
  • fetal magnetocardiography
  • long QT syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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