Abstract
In the past 40 years, disordered mineral metabolism has been among the most intensely studied areas of nephrology. A June 2010 PubMed search for secondary hyperparathyroidism and kidney disease yielded 5866 references. Among these are papers documenting the development and application of numerous therapeutic agentsincluding calcitriol, vitamin D analogs, phosphate binders, and cinacalcetthat remain in widespread use in the day-to-day management of dialysis patients worldwide. However, almost 6000 papers later, fundamental pathophysiological concepts remain unclear, particularly regarding the early pathogenesis of disordered mineral metabolism.
Original language | English (US) |
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Pages (from-to) | 947-949 |
Number of pages | 3 |
Journal | Kidney international |
Volume | 78 |
Issue number | 10 |
DOIs |
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State | Published - Nov 2010 |
ASJC Scopus subject areas
- Nephrology