Fibrin glue for the treatment of persistent lymphatic drainage

Warren G. Giberson, Patrick M. McCarthy, Bruce H. Kaufman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


A 7-year-old girl underwent resection of an abdominal wall lymphangiomatous tumor. Postoperative serous drainage, up to 300 mL per day, developed despite application of external pressure to the wound. Thirty-three days after the initial procedure, fibrin glue was applied to the draining tract. Concentrated fibrinogen was prepared from one unit of blood donated by the patient's mother. Ten milliliters fibrinogen and 10 mL thrombin (1,000 U/mL) were injected simultaneously through the wound drain as it was slowly removed, and pressure was reapplied for 48 hours. No further drainage occurred, and at 2- and 14-week follow-up examinations the wound had healed normally without reaccumulation of fluid. Fibrin glue successfully sealed this persistently draining abdominal wall tract. It is a painless, safe, and effective biologic sealant, and when prepared from homologous plasma it carries a low risk of virus transmission.

Original languageEnglish (US)
Pages (from-to)1188-1189
Number of pages2
JournalJournal of Pediatric Surgery
Issue number12
StatePublished - Jan 1 1988


  • Fibrin glue
  • lymphangioma
  • lymphatic drainage

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery


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