Fibromuscular dysplasia of the brachial artery: A case report and review of the literature

William W. Lin, Gregory S. McGee, Bruce K. Patterson, James S.T. Yao, William H. Pearce*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Fibromuscular dysplasia is a nonatherosclerotic, noninflammatory vascular disease that involves primarily medium-sized and small arteries. Fibromuscular dysplasia is characterized by medial fibrosis with or without smooth muscle cell hyperplasia and may produce luminal impingement with severe turbulence. Secondary aneurysmal deformity with or without thrombosis may also contribute to the obstruction. Fibromuscular dysplasia most commonly involves the renal and carotid arteries, with upper-extremity disease rarely reported. This case report describes a patient with digital embolization from brachial artery fibromuscular dysplasia. Angiography demonstrated significant narrowing and irregularity with a characteristic "string-of-beads" appearance of the right midbrachial artery. The abnormal segment was resected and reconstructed with a reversed saphenous vein graft. Histologic studies revealed disruption of the internal elastic lamina and disorientation of the hyperplastic medial smooth muscle cells characteristic of fibromuscular dysplasia.

Original languageEnglish (US)
Pages (from-to)66-70
Number of pages5
JournalJournal of Vascular Surgery
Volume16
Issue number1
DOIs
StatePublished - Jul 1992

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Fibromuscular dysplasia of the brachial artery: A case report and review of the literature'. Together they form a unique fingerprint.

Cite this