Fine-needle aspiration of metanephric adenoma of the kidney with clinical, radiographic and histopathologic correlation: A review

Luis Z. Blanco*, Caitlin O. Schein, Tushar Patel, Dawn E. Heagley, David J. Cimbaluk, Vijaya Reddy, Paolo Gattuso

*Corresponding author for this work

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Metanephric adenoma of the kidney is an uncommon benign epithelial neoplasm with only a small number of reports that describe its cytologic features. We describe two additional cases of metanephric adenoma diagnosed on fine-needle aspiration biopsy and review the available literature. Our cases showed similar cytology and were composed of cellular smears with numerous clusters of small, oval to round cells arranged in a microfollicular pattern and papillary configurations. The tumor cells had scant cytoplasm, fine chromatin and absent nucleoli. Psamomma bodies, nuclear atypia, cellular cpleomorphism, necrosis, and mitoses were absent. Because of the rarity of this tumor and the common cytologic features it shares with other lesions, including malignant tumors such as Wilms' tumor and papillary renal cell carcinoma, awareness of the cytologic features of metanephric adenoma may aid in avoiding a diagnosis of malignancy, especially preoperatively, and in guiding the proper management for the patients.

Original languageEnglish (US)
Pages (from-to)742-751
Number of pages10
JournalDiagnostic cytopathology
Volume41
Issue number8
DOIs
StatePublished - Mar 4 2013

Keywords

  • cytologic features
  • fine-needle aspiration
  • kidney
  • metanephric adenoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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