First report of mild Brazilian spotted fever associated to arthritis

Virgínia Lucia Nazario Bonoldi, Roberta Gonçalves Marangoni, Giancarla Gauditano, Jonas Moraes-Filho, Marcelo Bahia Labruna, Natalino Hajime Yoshinari*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We describe the first Brazilian case of mild Rickettsiosis, complicated by knee monoarthritis, in young adult bitten by a tick on his left leg in Camburi zone, located in São Sebastião municipality, southern coastal region of the State of São Paulo, in the Atlantic rainforest region, Brazil. The patient developed inoculation eschar at the tick bite site associated with enlarged lymph nodes in the left groin, fever, polyarthralgia, headache and macular rash. Twenty days after tick bite episode, he displayed monoarthritis in his right knee. The diagnosis of mild Rickettsiosis was established by sequential immunological analysis in serum and synovial fluid, using the indirect immunofluorescence (IF) assay for antibodies reactive with Rickettsia parkeri and Rickettsia rickettsii. The mild Rickettsiosis is an emerging zoonosis, that must be investigated by physicians, including rheumatologists, in patients that present macular rash, fever and eventually arthritis, after visiting the southern coastal Atlantic rainforest region in Brazil.

Original languageEnglish (US)
Pages (from-to)237-240
Number of pages4
JournalRevista Brasileira de Reumatologia
Issue number3
StatePublished - 2014


  • Arthritis
  • Brazilian spotted fever
  • Infectious arthritis
  • Mild rickettsiosis

ASJC Scopus subject areas

  • Rheumatology

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