Fluorescence Quenching by Redox Molecular Pumping

Xuesong Li, Arthur H.G. David, Long Zhang, Bo Song, Yang Jiao, Damien Sluysmans, Yunyan Qiu, Yong Wu, Xingang Zhao, Yuanning Feng, Lorenzo Mosca, J. Fraser Stoddart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Artificial molecular pumps (AMPs), inspired by the active cellular transport exhibited in biological systems, enable cargoes to undergo unidirectional motion, courtesy of molecular ratchet mechanisms in the presence of energy sources. Significant progress has been achieved, using alternatively radical interactions and Coulombic repulsive forces to create working AMPs. In an attempt to widen the range of these AMPs, we have explored the effect of molecular pumping on the photophysical properties of a collecting chain on a dumbbell incorporating a centrally located pyrene fluorophore and two terminal pumping cassettes. The AMP discussed here sequesters two tetracationic cyclophanes from the solution, generating a [3]rotaxane in which the fluorescence of the dumbbell is quenched. The research reported in this Article demonstrates that the use of pumping cassettes allows us to generate the [3]rotaxane in which the photophysical properties of fluorophores can be modified in a manner that cannot be achieved with a mixture of the dumbbell and ring components of the rotaxane on account of their weak binding in solution.

Original languageEnglish (US)
Pages (from-to)3572-3579
Number of pages8
JournalJournal of the American Chemical Society
Issue number8
StatePublished - Mar 2 2022

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry
  • Catalysis
  • Colloid and Surface Chemistry


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