TY - JOUR
T1 - fMRI of monkey visual cortex
AU - Stefanacci, Lisa
AU - Reber, Paul
AU - Costanza, Jennifer
AU - Wong, Eric
AU - Buxton, Richard
AU - Zola, Stuart
AU - Squire, Larry
AU - Albright, Thomas
N1 - Funding Information:
We thank Mario Tengco and Cecelia and Jeff Manzanares for assistance in the design and construction of the primate chair, Jamie Simon for graphics assistance, and Marty Sereno for use of the nView video projector. This project was supported, in part, by a grant from the National Eye Institute (T. D. A.), by the National Institutes of Health (5 T32 MH18399 [L. S.]), and by the McDonnell-Pew Center for Cognitive Neuroscience at San Diego by the Medical Research Service of the Department of Veterans Affairs (S. Z. and L. R. S.). T. D. A. is an Investigator of the Howard Hughes Medical Institute.
PY - 1998/6
Y1 - 1998/6
N2 - While functional magnetic resonance imaging (fMRI) is now used widely for demonstrating neural activity-related signals associated with perceptual, motor, and cognitive processes in humans, to date this technique has not been developed for use with nonhuman primates. fMRI in monkeys offers a potentially valuable experimental approach for investigating brain function, which will complement and aid existing techniques such as electrophysiology and the behavioral analysis of the effects of brain lesions. There are, however, a number of significant technical challenges involved in using fMRI with monkeys. Here, we describe the procedures by which we have overcome these challenges to carry out successful fMRI experiments in an alert monkey, and we present the first evidence of activity-related fMRI signals from monkey cerebral cortex.
AB - While functional magnetic resonance imaging (fMRI) is now used widely for demonstrating neural activity-related signals associated with perceptual, motor, and cognitive processes in humans, to date this technique has not been developed for use with nonhuman primates. fMRI in monkeys offers a potentially valuable experimental approach for investigating brain function, which will complement and aid existing techniques such as electrophysiology and the behavioral analysis of the effects of brain lesions. There are, however, a number of significant technical challenges involved in using fMRI with monkeys. Here, we describe the procedures by which we have overcome these challenges to carry out successful fMRI experiments in an alert monkey, and we present the first evidence of activity-related fMRI signals from monkey cerebral cortex.
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U2 - 10.1016/S0896-6273(00)80485-7
DO - 10.1016/S0896-6273(00)80485-7
M3 - Article
C2 - 9655492
AN - SCOPUS:0032103432
VL - 20
SP - 1051
EP - 1057
JO - Neuron
JF - Neuron
SN - 0896-6273
IS - 6
ER -