Fosamprenavir

Suzanne M. Crowe, Christine Katlama, Robert Murphy

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Fosamprenavir is a sulfa-containing calcium phosphate ester prodrug of amprenavir. Like other HIV-1 protease inhibitors, amprenavir binds to the active site of the HIV-1 protease. This prevents the processing of viral Gag and Gag-Pol polyprotein precursors, resulting in the formation of immature noninfectious viral particles.

Original languageEnglish (US)
Title of host publicationKucers the Use of Antibiotics
Subtitle of host publicationA Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition
PublisherCRC Press
Pages4104-4124
Number of pages21
ISBN (Electronic)9781498747967
ISBN (Print)9781498747950
DOIs
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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