Abstract
Fosamprenavir is a sulfa-containing calcium phosphate ester prodrug of amprenavir. Like other HIV-1 protease inhibitors, amprenavir binds to the active site of the HIV-1 protease. This prevents the processing of viral Gag and Gag-Pol polyprotein precursors, resulting in the formation of immature noninfectious viral particles.
| Original language | English (US) |
|---|---|
| Title of host publication | Kucers the Use of Antibiotics |
| Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs, Seventh Edition |
| Publisher | CRC Press |
| Pages | 4104-4124 |
| Number of pages | 21 |
| ISBN (Electronic) | 9781498747967 |
| ISBN (Print) | 9781498747950 |
| DOIs | |
| State | Published - Jan 1 2017 |
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- General Medicine
