Frequency dependence of backscatter coefficient versus scatterer volume fraction

Jian Feng Chen; James A. Zagzebski

doi:10.1109/58.489390

Frequency dependence of backscatter coefficient versus scatterer volume fraction

Jian Feng Chen^*, James A. Zagzebski

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Various groups are using the frequency dependence of backscattering to characterize tissue. In most cases, sparse scatterer concentrations are assumed in relating scattering parameters to tissue properties. This study addresses the relationship between backscatter frequency dependence and scatterer volume fraction. Backscatter coefficients (BSC) in the 2.5 to 9.0 MHz frequency range were measured for agar-gel phantoms containing Sephadex scatterers (mean diameter 42 //m) at volume fractions ranging from 5 to 50%. The BSC increased with scatterer volume fraction at low scatterer concentrations; at higher concentrations, the BSC reached a maximum with concentration and then decreased with yet increasing scatterer concentrations, as has been noted by previous authors. In addition, the volume fraction for the maximum backscatter coefficient varied with frequency, generally being greater at higher frequencies than lower frequencies, and the frequency dependence of the backscatter coefficient was greater for the higher scatterer concentrations than for the lower concentrations. These results are predicted by continuum models, where the spatial autocorrelation function depends on scatterer volume fraction.

Original language	English (US)
Pages (from-to)	345-353
Number of pages	9
Journal	IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Volume	43
Issue number	3
DOIs	https://doi.org/10.1109/58.489390
State	Published - 1996

Funding

Manuscript received May 31, 1994; revised December 12, 1994. This work was supported in part by a University of Wisconsin-Madison Medical Physics Department, Richard B. Mazess Advanced Fellowship, and by NIH Grant R01-CA39224. J.-F. Chen was with the Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706 USA. He is now with Siemens Medical Systems, Inc., Issaquah, WA 98027-7002 USA. J. A. Zagzebski is with the Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706 USA (e-mail: jimzag @macc.wisc.edu). Publisher Item Identifier S 0885-3010(96)03536-8.

ASJC Scopus subject areas

Instrumentation
Acoustics and Ultrasonics
Electrical and Electronic Engineering

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10.1109/58.489390

Cite this

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title = "Frequency dependence of backscatter coefficient versus scatterer volume fraction",

abstract = "Various groups are using the frequency dependence of backscattering to characterize tissue. In most cases, sparse scatterer concentrations are assumed in relating scattering parameters to tissue properties. This study addresses the relationship between backscatter frequency dependence and scatterer volume fraction. Backscatter coefficients (BSC) in the 2.5 to 9.0 MHz frequency range were measured for agar-gel phantoms containing Sephadex scatterers (mean diameter 42 //m) at volume fractions ranging from 5 to 50%. The BSC increased with scatterer volume fraction at low scatterer concentrations; at higher concentrations, the BSC reached a maximum with concentration and then decreased with yet increasing scatterer concentrations, as has been noted by previous authors. In addition, the volume fraction for the maximum backscatter coefficient varied with frequency, generally being greater at higher frequencies than lower frequencies, and the frequency dependence of the backscatter coefficient was greater for the higher scatterer concentrations than for the lower concentrations. These results are predicted by continuum models, where the spatial autocorrelation function depends on scatterer volume fraction.",

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note = "Funding Information: Manuscript received May 31, 1994; revised December 12, 1994. This work was supported in part by a University of Wisconsin-Madison Medical Physics Department, Richard B. Mazess Advanced Fellowship, and by NIH Grant R01-CA39224. J.-F. Chen was with the Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706 USA. He is now with Siemens Medical Systems, Inc., Issaquah, WA 98027-7002 USA. J. A. Zagzebski is with the Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 53706 USA (e-mail: jimzag @macc.wisc.edu). Publisher Item Identifier S 0885-3010(96)03536-8.",

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N2 - Various groups are using the frequency dependence of backscattering to characterize tissue. In most cases, sparse scatterer concentrations are assumed in relating scattering parameters to tissue properties. This study addresses the relationship between backscatter frequency dependence and scatterer volume fraction. Backscatter coefficients (BSC) in the 2.5 to 9.0 MHz frequency range were measured for agar-gel phantoms containing Sephadex scatterers (mean diameter 42 //m) at volume fractions ranging from 5 to 50%. The BSC increased with scatterer volume fraction at low scatterer concentrations; at higher concentrations, the BSC reached a maximum with concentration and then decreased with yet increasing scatterer concentrations, as has been noted by previous authors. In addition, the volume fraction for the maximum backscatter coefficient varied with frequency, generally being greater at higher frequencies than lower frequencies, and the frequency dependence of the backscatter coefficient was greater for the higher scatterer concentrations than for the lower concentrations. These results are predicted by continuum models, where the spatial autocorrelation function depends on scatterer volume fraction.

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Frequency dependence of backscatter coefficient versus scatterer volume fraction

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