From primary structure to function: Biological insights from large-molecule mass spectra

Neil L. Kelleher*

*Corresponding author for this work

Research output: Contribution to journalReview article

27 Scopus citations

Abstract

As increasing information is available from genomic databases, mass spectrometry has begun to be used to identify and/or assess regions of predicted DNA or protein sequence. Mass spectrometry performance limits, together with experiments designed for genomic interplay, are being extended to allow accurate genotyping and protein profiling of cells at rates commensurate with the data-intensive future of biology.

Original languageEnglish (US)
JournalChemistry and Biology
Volume7
Issue number2
DOIs
StatePublished - Feb 1 2000

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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