TY - JOUR
T1 - Frontal alpha EEG asymmetry before and after behavioral activation treatment for depression
AU - Gollan, Jackie K.
AU - Hoxha, Denada
AU - Chihade, Dietta
AU - Pflieger, Mark E.
AU - Rosebrock, Laina
AU - Cacioppo, John
N1 - Funding Information:
The preparation for this manuscript was supported by Grant R21 MH082133-01A1 (Gollan: PI) from the National Institute of Mental Health . The funding source did not have any involvement in the design, data collection, analysis, or interpretation of this study. Drs. Denada Hoxha, Jon Sutton, Jordana Segal-Goldstein, Patrick Nowlin served as research clinicians. Sarah Getch and Kallio Hunnicutt-Ferguson served as coordinators. Bjorn Hanson, Angel Buchanan, Shandra Brown, Justin Birnholz, Noah Yulish, Michal Rischall, and Lindsey Sankin conducted phone screens and clinical interviews. Bjorn Hanson and Justin Birnholz conducted adherence ratings. Rebecca Shor and Sara Polis conducted physiological assessments. Ruth Herman Dunn and Christopher Martell provided off-site BA competency reviews. Demetrios Voreades, Applications Engineer from Source Signal Imaging, Inc. generated the topographies using the EMSE 5.5.1 program.
PY - 2014/5
Y1 - 2014/5
N2 - Background: Mid-frontal and mid-lateral (F3/F4 and F7/F8) EEG asymmetry has been associated with motivation and affect. We examined alpha EEG asymmetry in depressed and healthy participants before and after Behavioral Activation treatment for depression; examined the association between alpha EEG asymmetry and motivational systems and affect; and evaluated the utility of alpha EEG asymmetry in predicting remission. Methods: Depressed (n=. 37) and healthy participants (n=. 35) were assessed before and after treatment using a clinical interview, a task to measure baseline EEG, and questionnaires of behavioral activation and inhibition, avoidance, and affect. Results: Alpha EEG asymmetry was significantly higher in depressed than healthy participants at pre-treatment, positively correlated with negative affect and behavioral inhibition, and inversely correlated with lower behavioral activation sensitivity. Conclusions: Heightened alpha EEG asymmetry in depressed participants was significantly associated with increased behavioral inhibition and negative emotion and was independent of clinical remission.
AB - Background: Mid-frontal and mid-lateral (F3/F4 and F7/F8) EEG asymmetry has been associated with motivation and affect. We examined alpha EEG asymmetry in depressed and healthy participants before and after Behavioral Activation treatment for depression; examined the association between alpha EEG asymmetry and motivational systems and affect; and evaluated the utility of alpha EEG asymmetry in predicting remission. Methods: Depressed (n=. 37) and healthy participants (n=. 35) were assessed before and after treatment using a clinical interview, a task to measure baseline EEG, and questionnaires of behavioral activation and inhibition, avoidance, and affect. Results: Alpha EEG asymmetry was significantly higher in depressed than healthy participants at pre-treatment, positively correlated with negative affect and behavioral inhibition, and inversely correlated with lower behavioral activation sensitivity. Conclusions: Heightened alpha EEG asymmetry in depressed participants was significantly associated with increased behavioral inhibition and negative emotion and was independent of clinical remission.
KW - Alpha EEG asymmetry
KW - Approach-related motivation
KW - Avoidance
KW - Behavioral Activation treatment
KW - Major depression
KW - Withdrawal-related motivation
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U2 - 10.1016/j.biopsycho.2014.03.003
DO - 10.1016/j.biopsycho.2014.03.003
M3 - Article
C2 - 24674708
AN - SCOPUS:84899830956
SN - 0019-493X
VL - 99
SP - 198
EP - 208
JO - Biological Psychology
JF - Biological Psychology
IS - 1
ER -