Full-thickness skin grafts for hypospadias repair

Matthias Dominikus Hofer, Justin S. Han, Chris M. Gonzalez*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Grafting of tissue holds an important role for hypospadias repair and is necessary when there is insufficient native urethral tissue for reconstruction. Although buccal mucosa grafts have become the most widely used grafts for urethral reconstruction, there are situations where they may not be indicated. Revision or salvage hypospadias repairs in which prior buccal mucosa grafts have been harvested often require an alternative graft source, such as a full-thickness skin graft. Full-thickness skin grafts can commonly be obtained from penile skin, such as the prepuce if present or from other sites such as the postauricular or abdominal regions. The technical challenges of skin grafting are limited relative to other tissue types and use of such grafts applies to a variety of operative approaches and strategies of hypospadias repair. Although both one-and two-stage repairs can be performed with similar success rates, a two-staged approach provides certain distinct advantages, such as easier execution and better evaluation of graft take prior to construction of the neo-urethra. The clinical outcome of full-thickness skin grafting in patients, specifically in the long-term, is difficult to evaluate given the paucity of existing reports. Based on the data available, there is an approximately 80% success rate after the repair in the intermediate term. Although this rate is generally lower than with other grafts, it is mainly due to the challenging patient cohort for which full-thickness skin grafts are utilized and therefore well acceptable given these circumstances.

Original languageEnglish (US)
Title of host publicationHypospadias Surgery
Subtitle of host publicationChallenges and Limits
PublisherNova Science Publishers, Inc.
Number of pages17
ISBN (Electronic)9781633211414
ISBN (Print)9781633211384
StatePublished - Jul 1 2014

ASJC Scopus subject areas

  • General Medicine


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