Fun with maths: Exploring implications of mathematical models for malaria eradication

Philip A. Eckhoff*, Caitlin A. Bever, Jaline Li Gerardin, Edward A. Wenger

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Mathematical analyses and modelling have an important role informing malaria eradication strategies. Simple mathematical approaches can answer many questions, but it is important to investigate their assumptions and to test whether simple assumptions affect the results. In this note, four examples demonstrate both the effects of model structures and assumptions and also the benefits of using a diversity of model approaches. These examples include the time to eradication, the impact of vaccine efficacy and coverage, drug programs and the effects of duration of infections and delays to treatment, and the influence of seasonality and migration coupling on disease fadeout. An excessively simple structure can miss key results, but simple mathematical approaches can still achieve key results for eradication strategy and define areas for investigation by more complex models.

Original languageEnglish (US)
Article number486
JournalMalaria journal
Volume13
Issue number1
DOIs
StatePublished - Dec 11 2014

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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