Functional outcomes and quality of life in patients with brain tumours: A review of the literature

M. E. Huang*, J. Wartella, J. Kreutzer, W. Broaddus, L. Lyckholm

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations


Objective: To review the literature with respect to functional outcomes and quality of life as it pertains to individuals with brain tumours. Main outcomes: Most functional outcome papers have focused on acute inpatient rehabilitation. In general, patients with brain tumours have comparable rates of functional gains as other models of neurologic disability. Tumour type and concomitant treatment do not impact functional outcome. Functional independence may predict survivability in certain populations. Numerous instruments are used to measure the multiple facets of quality of life. Depression, anger and fatigue can impact both physical and psychological aspects of quality of life. The physical and functional aspects can vary depending on the tumour type. Treatment regimens can negatively impact quality of life. Conclusion: Brain tumour patients experience changes in function and quality of life during their disease course. Rehabilitation services may offer a unique opportunity to influence both functional outcome and more closely assess quality of life in these individuals.

Original languageEnglish (US)
Pages (from-to)843-856
Number of pages14
JournalBrain Injury
Issue number10
StatePublished - 2001

ASJC Scopus subject areas

  • Clinical Neurology
  • Developmental and Educational Psychology
  • Neuroscience (miscellaneous)


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