Functional outcomes and quality of life in peripheral arteria disease: Current status

Mark R. Nehler*, Mary M. McDermott, Diane Treat-Jacobson, Ian Chetter, Judith G. Regensteiner

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

100 Scopus citations


This review examines current evidence for baseline functional impairment and changes with therapy in patients with peripheral arterial disease (PAD) - ranging from patients without claudication or critical limb ischemia (CLI) but other exertional leg symptoms (erroneously referred to as asymptomatic in the Fontaine classification system), to patients with claudication and those with CLI. The review points out that the status of functional outcomes research is markedly different in focus and development in the different levels of disease severity - paradoxically less studied in the more severe CLI population than in patients with claudication, for example.

Original languageEnglish (US)
Pages (from-to)115-126
Number of pages12
JournalVascular Medicine
Issue number2
StatePublished - 2003


  • Critical limb ischemia
  • Intermittent claudication
  • Outcomes
  • Peripheral arterial disease
  • Quality of life

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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