Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration

Ebrahim Afshinnekoo, Ryan T. Scott, Matthew J. MacKay, Eloise Pariset, Egle Cekanaviciute, Richard Barker, Simon Gilroy, Duane Hassane, Scott M. Smith, Sara R. Zwart, Mayra Nelman-Gonzalez, Brian E. Crucian, Sergey A. Ponomarev, Oleg I. Orlov, Dai Shiba, Masafumi Muratani, Masayuki Yamamoto, Stephanie E. Richards, Parag A. Vaishampayan, Cem MeydanJonathan Foox, Jacqueline Myrrhe, Eric Istasse, Nitin Singh, Kasthuri Venkateswaran, Jessica A. Keune, Hami E. Ray, Mathias Basner, Jack Miller, Martha Hotz Vitaterna, Deanne M. Taylor, Douglas Wallace, Kathleen Rubins, Susan M. Bailey*, Peter Grabham, Sylvain V. Costes, Christopher E. Mason, Afshin Beheshti

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

An international group of spaceflight researchers detail how spaceflight affects human biology from the molecular to physiological level and identify key challenges for making space exploration compatible with human health.

Original languageEnglish (US)
Pages (from-to)1162-1184
Number of pages23
JournalCell
Volume183
Issue number5
DOIs
StatePublished - Nov 25 2020

Keywords

  • aerospace medicine
  • DNA damage
  • epigenetic
  • microbiome
  • mitochondria
  • multi-omics
  • oxidative stress
  • space biology
  • spaceflight
  • telomere

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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