Further studies on the flow of aqueous humor through microporous filters

C. R. Ethier, R. D. Kamm, M. Johnson, A. F. Pavao, P. J. Anderson

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


It has recently been shown that aqueous humor is able to obstruct flow through Nuclepore polycarbonate filters having flow dimensions similar to those found in the juxtacanalicular tissue (JCT). We undertook studies designed to identify the component(s) of aqueous humor responsible for this obstruction and to determine the mechanism of blockage. We conclude that aqueous humor contains two components (one of which is specific to aqueous) which, when simultaneously present, hydrophobically bind to microporous filters and lead to filter blockage. Some implications for aqueous humor flow through the JCT are briefly discussed.

Original languageEnglish (US)
Pages (from-to)739-746
Number of pages8
JournalInvestigative Ophthalmology and Visual Science
Issue number4
StatePublished - 1989

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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