Futility Sustains Memory T Cells

Samuel E. Weinberg, Navdeep S. Chandel*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalImmunity
Volume41
Issue number1
DOIs
StatePublished - Jul 17 2014

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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