Futility Sustains Memory T Cells

Samuel E. Weinberg; Navdeep S. Chandel

doi:10.1016/j.immuni.2014.06.009

Futility Sustains Memory T Cells

Samuel E. Weinberg, Navdeep S. Chandel^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Immunity
Volume	41
Issue number	1
DOIs	https://doi.org/10.1016/j.immuni.2014.06.009
State	Published - Jul 17 2014

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2014.06.009

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title = "Futility Sustains Memory T Cells",

abstract = "Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a {"}futile cycle{"} of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a {"}futile cycle{"} of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.",

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AB - Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

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Futility Sustains Memory T Cells

Abstract

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