Futility Sustains Memory T Cells

Samuel E. Weinberg, Navdeep Chandel*

*Corresponding author for this work

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalImmunity
Volume41
Issue number1
DOIs
StatePublished - Jul 17 2014

Fingerprint

Medical Futility
Fatty Acids
Substrate Cycling
T-Lymphocytes
Metabolome
Cell Survival
Adenosine Triphosphate
Immunity

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases
  • Immunology

Cite this

Weinberg, Samuel E. ; Chandel, Navdeep. / Futility Sustains Memory T Cells. In: Immunity. 2014 ; Vol. 41, No. 1. pp. 1-3.
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Futility Sustains Memory T Cells. / Weinberg, Samuel E.; Chandel, Navdeep.

In: Immunity, Vol. 41, No. 1, 17.07.2014, p. 1-3.

Research output: Contribution to journalShort survey

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AU - Weinberg, Samuel E.

AU - Chandel, Navdeep

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AB - Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue of Immunity, O'Sullivan etal. (2014) report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival. Memory Tcells display a distinct metabolic profile compared to effector Tcells. In this issue, O'Sullivan etal. report that memory Tcells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

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