Gabapentin: A new tool in the treatment of neuropathic pain

Robert N Harden

doi:10.1111/j.1600-0404.1999.tb07389.x

Gabapentin: A new tool in the treatment of neuropathic pain

Robert N Harden

Physical Medicine and Rehabilitation

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Abstract

Human neuropathic pain remains a prevalent and pervasive problem in our society. Pharmacologically there is also no single, uniformly well-tolerated drug that is reliably helpful. Gabapentin has emerged as a useful new tool based on the results of two large multicenter trials in models of human neuropathy. Gabapentin proved to be a significantly better analgesic than placebo, was well tolerated in the elderly population, and had a significant positive impact on several subjective and objective outcome measures. A discussion of the standard treatments and the studies supporting this new tool is the purpose of this review.

Original language	English (US)
Pages (from-to)	43-47
Number of pages	5
Journal	Acta Neurologica Scandinavica, Supplement
Volume	100
Issue number	173
DOIs	https://doi.org/10.1111/j.1600-0404.1999.tb07389.x
State	Published - 1999

Keywords

Diabetic peripheral neuropathy
Gabapentin
Neuropathic pain
Postherpetic neuralgia

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1600-0404.1999.tb07389.x

Cite this

@article{32a52cd9f4ba41b6aef736477a4bece6,

title = "Gabapentin: A new tool in the treatment of neuropathic pain",

abstract = "Human neuropathic pain remains a prevalent and pervasive problem in our society. Pharmacologically there is also no single, uniformly well-tolerated drug that is reliably helpful. Gabapentin has emerged as a useful new tool based on the results of two large multicenter trials in models of human neuropathy. Gabapentin proved to be a significantly better analgesic than placebo, was well tolerated in the elderly population, and had a significant positive impact on several subjective and objective outcome measures. A discussion of the standard treatments and the studies supporting this new tool is the purpose of this review.",

keywords = "Diabetic peripheral neuropathy, Gabapentin, Neuropathic pain, Postherpetic neuralgia",

author = "Harden, {Robert N}",

year = "1999",

doi = "10.1111/j.1600-0404.1999.tb07389.x",

language = "English (US)",

volume = "100",

pages = "43--47",

journal = "Acta psychiatrica et neurologica. Supplementum",

issn = "0065-1427",

publisher = "Wiley-Blackwell",

number = "173",

}

TY - JOUR

T1 - Gabapentin

T2 - A new tool in the treatment of neuropathic pain

AU - Harden, Robert N

PY - 1999

Y1 - 1999

N2 - Human neuropathic pain remains a prevalent and pervasive problem in our society. Pharmacologically there is also no single, uniformly well-tolerated drug that is reliably helpful. Gabapentin has emerged as a useful new tool based on the results of two large multicenter trials in models of human neuropathy. Gabapentin proved to be a significantly better analgesic than placebo, was well tolerated in the elderly population, and had a significant positive impact on several subjective and objective outcome measures. A discussion of the standard treatments and the studies supporting this new tool is the purpose of this review.

AB - Human neuropathic pain remains a prevalent and pervasive problem in our society. Pharmacologically there is also no single, uniformly well-tolerated drug that is reliably helpful. Gabapentin has emerged as a useful new tool based on the results of two large multicenter trials in models of human neuropathy. Gabapentin proved to be a significantly better analgesic than placebo, was well tolerated in the elderly population, and had a significant positive impact on several subjective and objective outcome measures. A discussion of the standard treatments and the studies supporting this new tool is the purpose of this review.

KW - Diabetic peripheral neuropathy

KW - Gabapentin

KW - Neuropathic pain

KW - Postherpetic neuralgia

UR - http://www.scopus.com/inward/record.url?scp=0032825398&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032825398&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0404.1999.tb07389.x

DO - 10.1111/j.1600-0404.1999.tb07389.x

M3 - Review article

C2 - 10819091

AN - SCOPUS:0032825398

SN - 0065-1427

VL - 100

SP - 43

EP - 47

JO - Acta psychiatrica et neurologica. Supplementum

JF - Acta psychiatrica et neurologica. Supplementum

IS - 173

ER -

Gabapentin: A new tool in the treatment of neuropathic pain

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this