Gabapentin [1-(aminomethyl)cyclohexaneacetic acid, C9H17NO2] is a zwitterion in the solid state. Its crystal structure involves extensive hydrogen bonding between the NH3+ and COO- groups of neighboring molecules. The structure of gabapentin monohydrate [1-(aminomethyl)cyclohexaneacetic acid monohydrate, C9H17NO2·H2O] also involves such hydrogen bonding and, in addition, has a hydrogen-bonding network comprising the water molecules and both the NH3+ and COO- groups.
|Original language||English (US)|
|Number of pages||3|
|Journal||Acta Crystallographica Section C: Crystal Structure Communications|
|State||Published - May 1 2001|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)