Gabapentin and gabapentin monohydrate

James A. Ibers*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Gabapentin [1-(aminomethyl)cyclohexaneacetic acid, C9H17NO2] is a zwitterion in the solid state. Its crystal structure involves extensive hydrogen bonding between the NH3+ and COO- groups of neighboring molecules. The structure of gabapentin monohydrate [1-(aminomethyl)cyclohexaneacetic acid monohydrate, C9H17NO2·H2O] also involves such hydrogen bonding and, in addition, has a hydrogen-bonding network comprising the water molecules and both the NH3+ and COO- groups.

Original languageEnglish (US)
Pages (from-to)641-643
Number of pages3
JournalActa Crystallographica Section C: Crystal Structure Communications
Issue number5
StatePublished - May 2001

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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