Galactokinase: Evidence for a new racial polymorphism

Thomas A. Tedesco*, Robert Bonow, Karen Miller, William J. Mellman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Activities of galactokinase and galactose-1-phosphate uridyltransferase in red cells were assayed in a mixed racial population of 645 pregnant women. The distribution of individual transferase activities for black subjects was the same as that for whites. In contrast, the distributions of individual galactokinase activities differed significantly in blacks and whites, the mean for the black population being 30 percent lower than the mean for the white population. The same racial difference was found when red cell galactokinase activity was examined in males and in newborns. Because low-, intermediate-, and high-galactokinase activities appear to segregate within several black families, this observed difference suggests a new, racially determined enzyme polymorphism.

Original languageEnglish (US)
Pages (from-to)176-178
Number of pages3
JournalScience
Volume178
Issue number4057
DOIs
StatePublished - Jan 1 1972

ASJC Scopus subject areas

  • General

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