Galactorrhea, oligo/amenorrhea, and hyperprolactinemia in patients with cr aniopharyngiomas

Leonard P. Kapcala, Mark E. Molitch*, Kalmon D. Post, Bruce J. Biller, Robert J. Prager, Ivor M D Jackson, Seymour Reichlin

*Corresponding author for this work

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

We report three patients with craniopharyngiomas who had galactorrhea, oligo/amenorrhea, and abnormal sellar tomograms, clinically suggesting the presence of a prolactinoma. One patient had an intrasellar craniopharyngioma (Rathke's cleft cyst) diagnosed during surgical exploration of the pituitary fossa for removal of a suspected prolactinoma, and two had suprasellar craniopharyngiomas whose presence was suspected on the basis of computed tomography. This finding emphasizes the importance of computed tomography in the evaluation of patients with the clinical presentation of a prolactinoma. In two patients, PRL levels were elevated before surgery and remained elevated after removal of the craniopharyngioma. In the third case, an initially normal serum PRL level became elevated after removal of the tumor.

Original languageEnglish (US)
Pages (from-to)798-800
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume51
Issue number4
DOIs
StatePublished - Oct 1980

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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